Evaluations of Tear Protein Markers in Dry Eye Disease: Repeatability of Measurement and Correlation with Disease
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Source: iovs .org
Purpose: To characterize tear protein markers in dry eye disease (DED). Methods: In this prospective study, based on Ocular Surface Disease Index© (OSDI) and corneal staining (CS), 95 DED patients (OSDI≥13) with increasing CS were enrolled into 3 severity groups: DE1 (CS7); 25 asymptomatic subjects with no CS were enrolled into control (OSDIcentrations of 43 protein markers were measured by multiplexed immunoassay.
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